منابع مشابه
Modeling the passive cardiac electrical conductivity during ischemia
A geometrical model of cardiac tissue was used to compute the bidomain conductivities. We simulated ischemic conditions by adapting the geometrical model to morphological and electrical changes reported in literature. The simulated changes included 1) expansion of capillaries 2) cell swelling and 3) the closure of gap junctions, which coincide with changes associated with the three phases of is...
متن کاملBiomarkers of Cardiac Ischemia
Cardiac ischemia occurs when there is a supply versus demand mismatch in coronary blood flow. In patients who present with unstable angina, ischemia occurs due to partial or total occlusion of a coronary artery due to plaque rupture. In stable angina however, there is progressive vascular occlusion resulting ultimately in a luminal stenosis of greater than 70%, impeding blood flow to the distal...
متن کاملReperfusion after Cardiac Ischemia
Varadarajan, Srinivasan G., Jianzhong An, Enis Novalija, Steven C. Smart, and David F. Stowe. Changes in [Na]i, compartmental [Ca ], and NADH with dysfunction after global ischemia in intact hearts. Am J Physiol Heart Circ Physiol 280: H280–H293, 2001.—We measured the effects of global ischemia and reperfusion on intracellular Na, NADH, cytosolic and mitochondrial (subscript mito) Ca, relaxatio...
متن کاملLocating Cardiac Ischemia
The paper describes an optimization problem of identifying heart ischemia using ECG measurements on the torso surface. Heart ischemia is a condition of reduced blood supply to cardiac tissue and can lead to heart infarctions. In the simulations, we model the cardiac electrical activity by a stationary form of the bidomain equations. These are solved using an adaptive finite element method on a ...
متن کاملCardiac MRI for myocardial ischemia.
Proper assessment of the physiologic impact of coronary artery stenosis on the LV myocardium can affect patient prognosis and treatment decisions. Cardiac magnetic resonance imaging (CMR) assesses myocardial perfusion by imaging the myocardium during a first-pass transit of an intravenous gadolinium bolus, with spatial and temporal resolution substantially higher than nuclear myocardial perfusi...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the New York Academy of Sciences
سال: 2006
ISSN: 0077-8923
DOI: 10.1196/annals.1380.029